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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM21A All Species: 17.58
Human Site: S688 Identified Species: 48.33
UniProt: Q641Q2 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q641Q2 NP_001005751.1 1341 147184 S688 Q K K T Q R V S L L F E D D V
Chimpanzee Pan troglodytes XP_001140122 1427 155633 S774 Q K K T Q R V S L L F E D D V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534948 1205 132612 N597 V T L P S S K N S K L L P E T
Cat Felis silvestris
Mouse Mus musculus Q6PGL7 1334 145292 S684 Q K K T Q R T S L L F E D D A
Rat Rattus norvegicus Q80X08 1328 145131 S681 Q K K T Q R T S L L F E D D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234527 1326 146323 S673 Q R K P Q R I S L L F E D D A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001039320 401 44860
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZBW7 1469 160880 T784 K N E P L V G T E N E D I K K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800027 2367 254413 A962 S S E G G G G A T P P E P P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.3 N.A. 65.9 N.A. 73.5 72.7 N.A. N.A. 55.4 N.A. 21.7 N.A. 20.4 N.A. N.A. 24.1
Protein Similarity: 100 92.6 N.A. 70.6 N.A. 80.5 80 N.A. N.A. 68.7 N.A. 26.2 N.A. 36.6 N.A. N.A. 36.2
P-Site Identity: 100 100 N.A. 0 N.A. 86.6 86.6 N.A. N.A. 73.3 N.A. 0 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 13.3 N.A. 86.6 86.6 N.A. N.A. 86.6 N.A. 0 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 23 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 12 56 56 0 % D
% Glu: 0 0 23 0 0 0 0 0 12 0 12 67 0 12 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 56 0 0 0 0 % F
% Gly: 0 0 0 12 12 12 23 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 12 0 0 0 0 0 12 0 0 % I
% Lys: 12 45 56 0 0 0 12 0 0 12 0 0 0 12 23 % K
% Leu: 0 0 12 0 12 0 0 0 56 56 12 12 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 0 0 0 0 0 12 0 12 0 0 0 0 0 % N
% Pro: 0 0 0 34 0 0 0 0 0 12 12 0 23 12 0 % P
% Gln: 56 0 0 0 56 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 12 0 0 0 56 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 12 0 0 12 12 0 56 12 0 0 0 0 0 0 % S
% Thr: 0 12 0 45 0 0 23 12 12 0 0 0 0 0 23 % T
% Val: 12 0 0 0 0 12 23 0 0 0 0 0 0 0 23 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _